Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables integrin binding activity. Involved in integrin-mediated signaling pathway; stress fiber assembly; and transforming growth factor beta receptor signaling pathway. Located in cell leading edge and focal adhesion. Part of integrin alphav-beta5 complex. Is active in glutamatergic synapse and synaptic membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and genitourinary system. Orthologous to human ITGB5 (integrin subunit beta 5).