Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits integrin binding activity. Involved in several processes, including brown fat cell differentiation; cell adhesion mediated by integrin; and filopodium assembly. Localizes to several cellular components, including basal plasma membrane; external side of plasma membrane; and hemidesmosome. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Used to study junctional epidermolysis bullosa Herlitz type. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and junctional epidermolysis bullosa with pyloric atresia. Orthologous to human ITGA6 (integrin subunit alpha 6).