Automated description from the Alliance of Genome Resources (Release 5.1.1)
Enables integrin binding activity. Involved in regulation of angiogenesis. Acts upstream of or within several processes, including cell-cell adhesion mediated by integrin; cell-substrate junction assembly; and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; eye; and genitourinary system. Orthologous to human ITGA5 (integrin subunit alpha 5).