Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables extracellular matrix binding activity. Acts upstream of or within cell-matrix adhesion. Located in external side of plasma membrane and focal adhesion. Is expressed in several structures, including early conceptus; genitourinary system; gut; hematopoietic system; and liver. Used to study platelet-type bleeding disorder 16. Human ortholog(s) of this gene implicated in Glanzmann's thrombasthenia; platelet-type bleeding disorder 16; thrombocytopenia; and von Willebrand's disease 1. Orthologous to human ITGA2B (integrin subunit alpha 2b).