Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including identical protein binding activity; signaling receptor activator activity; and signaling receptor binding activity. Involved in insulin receptor signaling pathway. Acts upstream of with a positive effect on receptor internalization. Located in cytosol. Is active in extracellular space. Is expressed in several structures, including gut; liver; trunk; and yolk sac. Human ortholog(s) of this gene implicated in diabetic retinopathy; glucose metabolism disease (multiple); insulinoma; and pancreatic cancer. Orthologous to human INS (insulin).