Automated description from the Alliance of Genome Resources
Exhibits IMP dehydrogenase activity. Involved in lymphocyte proliferation and purine nucleotide biosynthetic process. Predicted to localize to the cytosol and nucleus. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 11; retinitis pigmentosa; and retinitis pigmentosa 10. Orthologous to human IMPDH1 (inosine monophosphate dehydrogenase 1).