Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have cytokine receptor activity. Involved in several processes, including hematopoietic or lymphoid organ development; negative regulation of T cell mediated cytotoxicity; and positive regulation of T cell differentiation in thymus. Localizes to external side of plasma membrane. Is expressed in adrenal gland; brain; early conceptus; hemolymphoid system; and lymphatic system. Human ortholog(s) of this gene implicated in severe combined immunodeficiency and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human IL7R (interleukin 7 receptor).