Automated description from the Alliance of Genome Resources
Exhibits interleukin-1 binding activity and interleukin-1 receptor activity. Involved in negative regulation of cytokine production; negative regulation of interleukin-1-mediated signaling pathway; and negative regulation of protein processing. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in aggressive periodontitis. Is expressed in several structures, including dorsal aorta; gut; pituitary gland; reproductive system; and thymus. Orthologous to human IL1R2 (interleukin 1 receptor type 2).