Automated description from the Alliance of Genome Resources
Exhibits interleukin-1 binding activity; interleukin-1 receptor activity; and protease binding activity. Involved in several processes, including cytokine-mediated signaling pathway; positive regulation of interleukin-1-mediated signaling pathway; and positive regulation of neutrophil extravasation. Localizes to the external side of plasma membrane. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in systemic scleroderma and type 1 diabetes mellitus. Orthologous to human IL1R1 (interleukin 1 receptor type 1).