Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables iduronate-2-sulfatase activity. Involved in dermatan sulfate catabolic process and heparan sulfate proteoglycan catabolic process. Located in lysosome. Is active in lysosomal lumen. Is expressed in nervous system and neural retina. Used to study mucopolysaccharidosis II. Human ortholog(s) of this gene implicated in mucopolysaccharidosis II. Orthologous to human IDS (iduronate 2-sulfatase).