Automated description from the Alliance of Genome Resources (Release 3.1)
Exhibits protein folding chaperone; protein kinase binding activity; and tau protein binding activity. Contributes to protein kinase regulator activity. Involved in several processes, including axonogenesis; positive regulation of protein kinase B signaling; and regulation of cellular protein metabolic process. Localizes to several cellular components, including HSP90-CDC37 chaperone complex; growth cone; and neuronal cell body. Predicted to colocalize with COP9 signalosome. Is expressed in several structures, including branchial arch; central nervous system; eye; future brain; and placenta. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human HSP90AB1 (heat shock protein 90 alpha family class B member 1).