Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific double-stranded DNA binding activity. Involved in several processes, including cellular response to ethanol; cellular response to retinoic acid; and nervous system development. Predicted to localize to nucleoplasm. Is expressed in several structures, including brain; embryo ectoderm; embryo mesenchyme; genitourinary system; and gut. Used to study Athabaskan brainstem dysgenesis syndrome. Human ortholog(s) of this gene implicated in Athabaskan brainstem dysgenesis syndrome and autistic disorder. Orthologous to human HOXA1 (homeobox A1).