Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have several functions, including amine binding activity; hydroxymethylbilane synthase activity; and uroporphyrinogen-III synthase activity. Predicted to be involved in heme biosynthetic process; liver development; and response to drug. Predicted to colocalize with condensed chromosome. Is expressed in several structures, including alimentary system; genitourinary system; liver; nose; and telencephalon. Used to study acute intermittent porphyria. Human ortholog(s) of this gene implicated in acute intermittent porphyria and sickle cell anemia. Orthologous to human HMBS (hydroxymethylbilane synthase).