Automated description from the Alliance of Genome Resources
Predicted to have several functions, including amine binding activity; hydroxymethylbilane synthase activity; and uroporphyrinogen-III synthase activity. Predicted to be involved in heme biosynthetic process. Predicted to colocalize with the condensed chromosome. Used to study acute intermittent porphyria. Human ortholog(s) of this gene implicated in acute intermittent porphyria and sickle cell anemia. Is expressed in several structures, including alimentary system; genitourinary system; liver; nose; and telencephalon. Orthologous to human HMBS (hydroxymethylbilane synthase).