Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 8.2.0)

Enables ErbB-2 class receptor binding activity and chemorepellent activity. Involved in several processes, including ERBB signaling pathway; nervous system development; and postsynapse to nucleus signaling pathway. Acts upstream of or within several processes, including nervous system development; positive regulation of intracellular signal transduction; and regulation of macromolecule metabolic process. Located in several cellular components, including axon; neuromuscular junction; and plasma membrane. Is active in several cellular components, including GABA-ergic synapse; mossy fiber rosette; and synaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in several diseases, including cannabis dependence; cerebrovascular disease (multiple); neurodegenerative disease (multiple); psychotic disorder (multiple); and substance abuse (multiple). Orthologous to human NRG1 (neuregulin 1).

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Gene Ontology Evidence Code Abbreviations:

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