Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits ErbB-2 class receptor binding activity and chemorepellent activity. Involved in several processes, including nervous system development; positive regulation of intracellular signal transduction; and positive regulation of protein phosphorylation. Localizes to several cellular components, including GABA-ergic synapse; axolemma; and glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease; dementia; middle cerebral artery infarction; myocardial infarction; and psychotic disorder (multiple). Orthologous to human NRG1 (neuregulin 1).