Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits epidermal growth factor receptor binding activity; growth factor activity; and heparin binding activity. Involved in several processes, including positive regulation of keratinocyte migration; positive regulation of smooth muscle cell proliferation; and wound healing, spreading of epidermal cells. Localizes to extracellular space and integral component of plasma membrane. Is expressed in several structures, including branchial arch; heart; oral region gland; telencephalon; and tooth. Human ortholog(s) of this gene implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. Orthologous to human HBEGF (heparin binding EGF like growth factor).