Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have endopeptidase inhibitor activity. Involved in several processes, including creatinine homeostasis; inflammatory response to wounding; and neutrophil homeostasis. Predicted to localize to membrane attack complex. Is expressed in several structures, including brain; liver; neural ectoderm; and otocyst. Human ortholog(s) of this gene implicated in several diseases, including asthma; complement component 5 deficiency; liver cirrhosis; neutropenia; and paroxysmal nocturnal hemoglobinuria. Orthologous to human C5 (complement C5).