Automated description from the Alliance of Genome Resources (Release 4.1.0)
Predicted to enable endopeptidase inhibitor activity. Involved in positive regulation of angiogenesis. Acts upstream of or within several processes, including creatinine homeostasis; inflammatory response to wounding; and neutrophil homeostasis. Predicted to be located in extracellular space. Predicted to be part of membrane attack complex. Is expressed in several structures, including alimentary system; central nervous system; future brain; otocyst; and respiratory system. Human ortholog(s) of this gene implicated in several diseases, including complement component 5 deficiency; liver cirrhosis; neutropenia; paroxysmal nocturnal hemoglobinuria; and pneumonia. Orthologous to human C5 (complement C5).