Automated description from the Alliance of Genome Resources
Exhibits MHC class I protein binding activity and peptide antigen binding activity. Involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; antigen processing and presentation of exogenous peptide antigen via MHC class I; and positive regulation of T cell mediated cytotoxicity. Localizes to the external side of plasma membrane. Used to study myositis. Human ortholog(s) of this gene implicated in Stevens-Johnson syndrome; allergic asthma; human immunodeficiency virus infectious disease; and psoriasis. Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A).