Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits NMDA glutamate receptor activity and calcium channel activity. Predicted to contribute to extracellularly glutamate-gated ion channel activity and ionotropic glutamate receptor activity. Involved in several processes, including learning or memory; long-term synaptic potentiation; and response to amphetamine. Localizes to several cellular components, including NMDA selective glutamate receptor complex; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including central nervous system; eye; hindlimb phalanx; intestine; and limb mesenchyme. Human ortholog(s) of this gene implicated in Huntington's disease; bipolar disorder; and schizophrenia. Orthologous to human GRIN2A (glutamate ionotropic receptor NMDA type subunit 2A).