Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables glutathione-disulfide reductase (NADP) activity. Acts upstream of or within cellular oxidant detoxification. Located in external side of plasma membrane. Is expressed in brain ventricular layer; gut; lung; metanephros; and retina. Human ortholog(s) of this gene implicated in cataract and macular degeneration. Orthologous to human GSR (glutathione-disulfide reductase).