Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables glucose-6-phosphate isomerase activity. Involved in gluconeogenesis. Acts upstream of or within several processes, including erythrocyte homeostasis; glucose homeostasis; and glycolytic process. Located in ciliary membrane. Is active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; metanephros; respiratory system; and sensory organ. Used to study congenital nonspherocytic hemolytic anemia. Human ortholog(s) of this gene implicated in congenital hemolytic anemia; congenital nonspherocytic hemolytic anemia; intellectual disability; and neuromuscular disease. Orthologous to human GPI (glucose-6-phosphate isomerase).