Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have several functions, including PDZ domain binding activity; chaperone binding activity; and signaling receptor binding activity. Involved in several processes, including circulatory system development; nervous system development; and reproductive structure development. Localizes to several cellular components, including brush border membrane; clathrin-coated pit; and cytoplasmic vesicle. Is expressed in several structures, including egg cylinder; metanephros; neural plate; ureter; and ventricular layer. Used to study Donnai-Barrow syndrome; Fanconi syndrome; and degenerative myopia. Human ortholog(s) of this gene implicated in Donnai-Barrow syndrome and autoimmune thyroiditis. Orthologous to human LRP2 (LDL receptor related protein 2).