Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Slc6a9. (This text reflects annotations as of Wednesday, January 23, 2013.)

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Summary text based on GO annotations supported by experimental evidence in mouse

• Researchers have inferred from direct assay, that the gene product of Slc6a9
  • participates in the following biological processes:
    • amino acid transmembrane transport ^[2]
    • glycine transport ^[2]
  • performs the following molecular functions:
    • glycine transmembrane transporter activity ^[2]
  • is located in the following cellular components:
    • plasma membrane ^[1]
• Based on the experimental annotations above, MGI curators have inferred, that the gene product of Slc6a9
  • is located in the following cellular components:
    • integral to membrane ^[2]

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Summary text based on GO annotations supported by structural data

• Slc6a9 encodes a protein or proteins that contain the following InterPro domains: Sodium:neurotransmitter symporter, Sodium:neurotransmitter symporter, glycine, type 1, indicating that the gene product:
  • participates in the following biological processes:
    • neurotransmitter transport
  • performs the following molecular functions:
    • neurotransmitter:sodium symporter activity
    • sodium:amino acid symporter activity
  • is located in the following cellular components:
    • integral to plasma membrane
    • membrane

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Summary text for additional MGI annotations

• Automated translation to GO terms of SwissProt keywords that describe Slc6a9 indicates that it:
  • participates in the following biological processes:
    • amino acid transport
    • neurotransmitter transport
    • transport
  • performs the following molecular functions:
    • symporter activity
  • is located in the following cellular components:
    • membrane

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References

1. Bassett EA et al. (2007) Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development. Mol Cell Biol, 27:7497-510. (PubMed:17724084)
2. Liu QR et al. (1992) Cloning and expression of a glycine transporter from mouse brain. FEBS Lett, 305:110-4. (PubMed:1618338)

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Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

ISO Inferred from sequence orthology

ISA Inferred from sequence alignment

ISM Inferred from sequence model

NAS Non-traceable author statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

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