Automated description from the Alliance of Genome Resources
Exhibits extracellularly glycine-gated chloride channel activity; glycine binding activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity and extracellular ligand-gated ion channel activity. Involved in several processes, including adult walking behavior; gamma-aminobutyric acid receptor clustering; and righting reflex. Localizes to the GABA-ergic synapse; glycinergic synapse; and membrane. Used to study hyperekplexia 2. Human ortholog(s) of this gene implicated in hyperekplexia 2. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skeleton. Orthologous to human GLRB (glycine receptor beta).