Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including dynein light chain binding activity; glutamine synthetase activity; and ion binding activity. Involved in regulation of endothelial cell migration and regulation of sprouting angiogenesis. Acts upstream of or within cellular response to starvation and response to glucose. Located in cell body; cytoplasm; and glial cell projection. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; sensory organ; and urinary system. Used to study temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; heart disease; and temporal lobe epilepsy. Orthologous to human GLUL (glutamate-ammonia ligase).