Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; promoter-specific chromatin binding activity; and transcription factor binding activity. Involved in several processes, including animal organ development; chordate embryonic development; and positive regulation of nervous system development. Localizes to the cilium; membrane; and nuclear speck. Human ortholog(s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Orthologous to human GLI2 (GLI family zinc finger 2).