Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have gap junction channel activity. Involved in placenta development. Localizes to cytoplasm and gap junction. Is expressed in several structures, including ear; early conceptus; reproductive system; rhombomere; and skin. Used to study erythrokeratodermia variabilis. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 2B; autosomal recessive nonsyndromic deafness 1A; erythrokeratodermia variabilis; and erythrokeratodermia variabilis et progressiva 1. Orthologous to human GJB3 (gap junction protein beta 3).