Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits growth hormone receptor activity and peptide hormone binding activity. Involved in several processes, including growth hormone receptor signaling pathway; positive regulation of peptidyl-tyrosine phosphorylation; and taurine metabolic process. Localizes to extrinsic component of membrane; nucleus; and plasma membrane. Used to study Laron syndrome. Human ortholog(s) of this gene implicated in several diseases, including Laron syndrome; familial hypercholesterolemia; isolated growth hormone deficiency; osteoarthritis; and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Orthologous to human GHR (growth hormone receptor).