Automated description from the Alliance of Genome Resources
Exhibits growth hormone receptor binding activity. Involved in cellular response to insulin stimulus; positive regulation of growth; and response to food. Localizes to several cellular components, including the extracellular space; secretory granule; and trans-Golgi network. Used to study isolated growth hormone deficiency type II. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune polyendocrine syndrome type 1; beta thalassemia; isolated growth hormone deficiency (multiple); and progeria. Is expressed in blood; brain; and male reproductive system. Orthologous to several human genes including GH1 (growth hormone 1).