Automated description from the Alliance of Genome Resources
Predicted to have BMP binding activity; identical protein binding activity; and signaling receptor binding activity. Involved in several processes, including limb morphogenesis; negative regulation of mesenchymal cell apoptotic process; and positive regulation of chondrocyte differentiation. Predicted to localize to the extracellular space. Used to study bone disease (multiple). Human ortholog(s) of this gene implicated in Parkinson's disease; bone disease (multiple); and proximal symphalangism. Is expressed in several structures, including connective tissue; heart; limb; metanephros; and skeleton. Orthologous to human GDF5 (growth differentiation factor 5).