Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II core promoter sequence-specific DNA binding activity; and RNA polymerase II transcription factor binding activity. Involved in several processes, including branching involved in blood vessel morphogenesis; nervous system development; and neural crest cell migration. Localizes to the nucleus. Is expressed in several structures, including 1st branchial arch; central nervous system; ear; embryo ectoderm; and reproductive system. Orthologous to human GBX2 (gastrulation brain homeobox 2).