Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including embryonic morphogenesis; heart development; and negative regulation of cell death. Localizes to the nuclear chromatin. Used to study atrial heart septal defect 2 and congenital diaphragmatic hernia. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4).