Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II transcription factor binding activity. Involved in several processes, including hemopoiesis; regulation of cellular macromolecule biosynthetic process; and regulation of erythrocyte differentiation. Localizes to the nucleus. Used to study myelodysplastic syndrome; myelofibrosis; and thrombocytopenia. Human ortholog(s) of this gene implicated in Down syndrome; beta thalassemia; and transient myeloproliferative syndrome. Is expressed in several structures, including alimentary system; central nervous system; ear; early conceptus; and genitourinary system. Orthologous to human GATA1 (GATA binding protein 1).