Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential. Acts upstream of or within G protein-coupled receptor signaling pathway and regulation of presynaptic membrane potential. Is active in GABA-ergic synapse and Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in autistic disorder and developmental and epileptic encephalopathy 45. Orthologous to human GABRB1 (gamma-aminobutyric acid type A receptor subunit beta1).