Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have extracellular matrix structural constituent. Involved in several processes, including bone trabecula formation; positive regulation of ossification; and sequestering of TGFbeta in extracellular matrix. Localizes to microfibril. Used to study distal arthrogryposis. Human ortholog(s) of this gene implicated in congenital contractural arachnodactyly and scoliosis. Is expressed in several structures, including connective tissue; embryo mesenchyme; genitourinary system; heart; and respiratory system. Orthologous to human FBN2 (fibrillin 2).