Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to be an extracellular matrix structural constituent. Involved in several processes, including bone trabecula formation; positive regulation of osteoblast differentiation; and sequestering of TGFbeta in extracellular matrix. Localizes to extracellular region and microfibril. Is expressed in several structures, including connective tissue; embryo mesenchyme; genitourinary system; heart; and respiratory system. Used to study distal arthrogryposis. Human ortholog(s) of this gene implicated in congenital contractural arachnodactyly and scoliosis. Orthologous to human FBN2 (fibrillin 2).