Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription factor activity; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and histone methyltransferase activity (H3-K9 specific). Involved in several processes, including animal organ development; embryonic limb morphogenesis; and regulation of transcription, DNA-templated. Localizes to the nucleus. Predicted to colocalize with the histone deacetylase complex. Used to study otitis media. Human ortholog(s) of this gene implicated in myeloid neoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human MECOM (MDS1 and EVI1 complex locus).