Automated description from the Alliance of Genome Resources
Predicted to contribute to DNA-dependent ATPase activity and RNA polymerase II CTD heptapeptide repeat kinase activity. Involved in several processes, including animal organ development; neurogenesis; and nucleic acid metabolic process. Localizes to the nucleus. Used to study photosensitive trichothiodystrophy and xeroderma pigmentosum group D. Human ortholog(s) of this gene implicated in several diseases, including acoustic neuroma; acquired immunodeficiency syndrome; endocrine gland cancer (multiple); hematologic cancer (multiple); and xeroderma pigmentosum (multiple). Is expressed in central nervous system; eye; hair follicle; and liver. Orthologous to human ERCC2 (ERCC excision repair 2, TFIIH core complex helicase subunit).