Automated description from the Alliance of Genome Resources
Predicted to have several functions, including neuregulin binding activity; protein heterodimerization activity; and transmembrane signaling receptor activity. Involved in several processes, including nervous system development; positive regulation of calcineurin-NFAT signaling cascade; and positive regulation of cardiac muscle tissue development. Localizes to the apical plasma membrane and lateral plasma membrane. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 2. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ epithelium. Orthologous to human ERBB3 (erb-b2 receptor tyrosine kinase 3).