Automated description from the Alliance of Genome Resources
Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including embryonic brain development; nervous system development; and regionalization. Predicted to localize to the RSC-type complex and membrane. Human ortholog(s) of this gene implicated in Parkinson's disease. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and limb. Orthologous to human EN1 (engrailed homeobox 1).