Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to gamma radiation; circadian regulation of gene expression; and regulation of cellular biosynthetic process. Localizes to the nucleus. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in asthma and myeloid neoplasm. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; genitourinary system; and jaw. Orthologous to human EGR1 (early growth response 1).