Automated description from the Alliance of Genome Resources
Exhibits epidermal growth factor binding activity and epidermal growth factor-activated receptor activity. Predicted to contribute to nitric-oxide synthase regulator activity. Involved in several processes, including animal organ development; positive regulation of cell population proliferation; and protein autophosphorylation. Localizes to several cellular components, including the basolateral plasma membrane; endocytic vesicle; and perinuclear region of cytoplasm. Used to study aortic valve disease. Human ortholog(s) of this gene implicated in several diseases, including breast carcinoma; colorectal cancer; lung cancer (multiple); pancreatic cancer; and prostate cancer. Is expressed in several structures, including alimentary system; brain; integumental system; limb; and respiratory system. Orthologous to human EGFR (epidermal growth factor receptor).
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