Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits endothelin A receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; animal organ development; and branching involved in blood vessel morphogenesis. Localizes to extracellular space. Is expressed in several structures, including branchial arch; cardiovascular system; central nervous system; gut; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); lung disease (multiple); obesity; obstructive sleep apnea; and rheumatoid arthritis. Orthologous to human EDN1 (endothelin 1).