Automated description from the Alliance of Genome Resources
Exhibits endothelin A receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; animal organ development; and branching involved in blood vessel morphogenesis. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); lung disease (multiple); obesity; obstructive sleep apnea; and rheumatoid arthritis. Is expressed in several structures, including branchial arch; cardiovascular system; central nervous system; gut; and sensory organ. Orthologous to human EDN1 (endothelin 1).