Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables beta-catenin binding activity and protein kinase binding activity. Involved in several processes, including protein stabilization; regulation of synaptic vesicle exocytosis; and synapse organization. Acts upstream of or within several processes, including embryonic morphogenesis; neuron projection morphogenesis; and regulation of protein phosphorylation. Located in several cellular components, including Schaffer collateral - CA1 synapse; clathrin-coated vesicle; and glutamatergic synapse. Part of Wnt signalosome. Is active in postsynaptic density. Colocalizes with cytoplasm. Is expressed in several structures, including central nervous system; early conceptus; eye; genitourinary system; and skin. Human ortholog(s) of this gene implicated in DiGeorge syndrome and autosomal dominant Robinow syndrome 2. Orthologous to human DVL1 (dishevelled segment polarity protein 1).