Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable pore-forming activity and protein homodimerization activity. Acts upstream of or within response to bacterium and response to xenobiotic stimulus. Located in extracellular space. Is expressed in crypt of Lieberkuhn of jejunum; ileum; and intestine. Orthologous to several human genes including DEFA1 (defensin alpha 1); DEFA1B (defensin alpha 1B); and DEFA3 (defensin alpha 3).