Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables cysteine-type deubiquitinase activity; cysteine-type endopeptidase activity; and ubiquitin protein ligase binding activity. Involved in axon extension and neuron migration. Acts upstream of or within several processes, including cellular response to transforming growth factor beta stimulus; in utero embryonic development; and nervous system development. Located in apical part of cell and cytoplasm. Is expressed in several structures, including central nervous system; eye; genitourinary system; limb interdigital region; and lung. Human ortholog(s) of this gene implicated in female-restricted syndromic X-linked intellectual disability 99 and non-syndromic X-linked intellectual disability 99. Orthologous to human USP9X (ubiquitin specific peptidase 9 X-linked).