Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II distal enhancer sequence-specific DNA binding activity. Involved in import into nucleus and negative regulation of transcription by RNA polymerase II. Localizes to the nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human BACH2 (BTB domain and CNC homolog 2).