Automated description from the Alliance of Genome Resources
Predicted to have identical protein binding activity; protease binding activity; and serine-type endopeptidase inhibitor activity. Involved in response to cytokine and response to peptide hormone. Localizes to the extracellular region. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Is expressed in gut; liver lobe; and metanephros. Orthologous to human SERPINA1 (serpin family A member 1).