Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in circadian regulation of gene expression; negative regulation of DNA-templated transcription; and response to cAMP. Acts upstream of or within glycosphingolipid metabolic process; positive regulation of transcription by RNA polymerase II; and spermatogenesis. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; lung; palatal shelf; testis; and ureter. Orthologous to human CREM (cAMP responsive element modulator).