Automated description from the Alliance of Genome Resources
Predicted to have G protein-coupled acetylcholine receptor activity; G protein-coupled serotonin receptor activity; and acetylcholine binding activity. Involved in several processes, including cholinergic synaptic transmission; positive regulation of smooth muscle contraction; and saliva secretion. Predicted to localize to the glutamatergic synapse; integral component of synaptic membrane; and neuron projection. Used to study megacystis-microcolon-intestinal hypoperistalsis syndrome. Human ortholog(s) of this gene implicated in bladder disease; chronic obstructive pulmonary disease; prune belly syndrome; and pulmonary fibrosis. Orthologous to human CHRM3 (cholinergic receptor muscarinic 3).