Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to contribute to serine-type endopeptidase activity. Predicted to be involved in several processes, including activation of plasma proteins involved in acute inflammatory response; positive regulation of macromolecule metabolic process; and positive regulation of signal transduction. Predicted to localize to several cellular components, including cell surface; extracellular space; and serine-type peptidase complex. Is expressed in several structures, including central nervous system; egg cylinder; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; COVID-19; disseminated intravascular coagulation; and von Willebrand's disease. Orthologous to human F3 (coagulation factor III, tissue factor).