Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables Hsp70 protein binding activity; chromatin binding activity; and cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within fibroblast proliferation; mitotic G2 DNA damage checkpoint signaling; and mitotic cell cycle phase transition. Part of cyclin A2-CDK1 complex. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer; cervical cancer; and urinary bladder cancer. Orthologous to human CDK1 (cyclin dependent kinase 1).